Rapid colorimetric assay for acetaminophen without salicylate or phenylephrine interference.

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Rapid colorimetric assay for acetaminophen without salicylate or phenylephrine interference.

A simple rapid, and economical procedure is presented for the quantitative determination of acetaminophen in serum. Acetaminophen is extracted into solvent, and, when back-extracted into base, is simultaneously reacted with Folin-Ciocalteau reagent to form a colored complex. The potential interference of bilirubin is eliminated by treatment with p-diazobenzene sulfonic acid. Results obtained wi...

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A rapid, simple acetaminophen determination is available.

contribution in the measurement. Concentration of active chemical ingredients , additives, timing parameters, and electronic time constants are variables that help to establish the positive characteristics and define the limitations of each method. To the Editor: We read with interest the recent Letter of Rosenbaum et al. (1) expressing their concerns about possible interference by salicylates ...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1982

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/28.5.1171